HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → PD-117596 hydrochloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | 1-Cyclopropyl-6,7,8-trifluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid | HCID 535414 | — |
| Reactant | 3-(2,2-Dimethylpropylideneamino)-pyrrolidine | HCID 14836604 | — |
| Product | PD-117596 hydrochloride | HCID 13590048 | — |
Reaction Steps
If, for example, 1-cyclopropyl-6,7,8-trifluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid is reacted with 3-(2,2-dimethylpropylideneamino)-pyrrolidine and the reaction product is treated with hydrochloric acid, 7-(3-amino-1-pyrrolidinyl)-1-cyclopropyl-6,8-difluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid hydrochloride is obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05723627 |
| Source dataset | uspto-grants-1998_03 |
| ORD ID | ord-269b34579b6543ad8b25187fc9fff0bb |
| Source note | uspto-grants-1998_03 |