HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Hydroxybenzaldehyde → 3,5-Difluoro-4-(4-formyl-phenoxy)benzonitrile
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Hydroxybenzaldehyde | HCID 126 | — |
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | 3,5-Difluorobenzonitrile | HCID 587204 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | 3,5-Difluoro-4-(4-formyl-phenoxy)benzonitrile | HCID 59729906 | — |
Reaction Steps
Basic displacement reaction of 4-hydroxy benzaldehyde and 3,5-difluorobenzonitrile using potassium carbonate in anhydrous DMF at reflux temperatures affords the above compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07381719B2 |
| Source dataset | uspto-grants-2008_06 |
| ORD ID | ord-d55c8c976bf24942bd21512f4eac3e70 |
| Source note | uspto-grants-2008_06 |