反应详情

The relative amounts of each individual isomer is dependent on the precise conditions used for their formation and whether the hydrogenation reaction is carried out on the mixture of isomers of 2-(2,4-dimethylcyclohex-3-en-1-yl)pyridine or an individual isomer thereof. For example, it has been found that when the hydrogenation reaction is performed on 2-[(1R,2S)-2,4-dimethylcyclohex-3-en-1-yl]pyridine, the major product formed in the resulting mixture of isomers of the pyridine of the invention is 2-[(1S,2R,4R)-2,4-dimethylcyclohexyl]pyridine. By contrast, hydrogenation of 2-[(1R,2R)-2,4-dimethylcyclohex-3-en-1-yl]pyridine conveniently gives a mixture of the 2-[(1R,2R,4R)-2,4-dimethylcyclohexyl]pyridine and 2-[(1R,2R,4S)-2,4-dimethylcyclohexyl]pyridine isomers as the major reaction product.

1. customused for their formation and whether the hydrogenation reaction
2. customthe hydrogenation reaction