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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 13110Generated: October 25, 2026

(1R,2S)-2-amino-1-phenylbutan-1-ol hydrochloride → (1R,2S)-1-(1-(4-fluorophenyl)-1H-indazol-5-yloxy)-1-phenylbutan-2-amine

https://huagongshe.com/reaction/13110

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(1R,2S)-2-amino-1-phenylbutan-1-ol hydrochlorideHCID 12562408—
Reactant(1R,2S)-(1-(4-fluorophenyl)-1H-indazol-5-yloxy)-1-phenylpentan-2-amineHCID 59339774—
Product(1R,2S)-1-(1-(4-fluorophenyl)-1H-indazol-5-yloxy)-1-phenylbutan-2-amineHCID 59339729—

Reaction Steps

was synthesised in the same way as (91a) from (1R,2S)-2-amino-1-phenylbutan-1-ol hydrochloride (95b, 53 mg, 0.26 mmol).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07728030B2
Source datasetuspto-grants-2010_06
ORD IDord-6352fbbb6f164325bb710eb96aa2da71
Source noteuspto-grants-2010_06