HCID 11216021, compound → HCID 11466879, compound

HRID 131102Notes

Reaction equation

HRID 131102 reaction equation
[CH:1]1C2NC3C(=CC=CC=3)SC=2C=[CH:3][C:2]=1[C:15](N[C@H](C(N[C@H](C(N[C@H](C(N[C@H]1CCOC1O)=O)CC(C)C)=O)CC(C)C)=O)CC(C)C)=O.[CH:48]1[C:61]2[NH:60][C:59]3[C:54](=[CH:55][CH:56]=[CH:57][CH:58]=3)[S:53][C:52]=2[CH:51]=[CH:50][C:49]=1[O:62][CH2:63][C:64]([NH:66][C@H:67]([C:72]([NH:74][C@H:75]([C:80]([NH:82][C@H:83]1[CH2:87][CH2:86][O:85][CH:84]1[O:88][CH3:89])=[O:81])CC(C)C)=[O:73])CC(C)C)=[O:65]>>[CH:48]1[C:61]2[NH:60][C:59]3[C:58](=[CH:57][CH:56]=[CH:55][CH:54]=3)[S:53][C:52]=2[CH:51]=[CH:50][C:49]=1[O:62][CH2:63][C:64]([NH:66][CH2:67][C:72]([N:74]([CH2:1][CH:2]([CH3:15])[CH3:3])[CH2:75][C:80]([NH:82][C@H:83]1[CH2:87][CH2:86][O:85][CH:84]1[O:88][CH3:89])=[O:81])=[O:73])=[O:65]

Participants

3

Reactant 2

HCID 11216021HCID 11216021, compoundHCID 11238764HCID 11238764, compound

Product 1

HCID 11466879HCID 11466879, compound

Procedure

The compounds of Examples 40 to 58 were prepared according to the experimental protocol described for the compound of Example 2 starting from the compounds of Examples 21 to 39 respectively.

Sources & evidence

ORD record
ord-be06e1747dec44a6bbd5af6a70ed2751
Source dataset
uspto-grants-2008_06
Patent number
US07384933B2

Reaction notes

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