HCID 11216021, compound → HCID 11238189, compound

HRID 131104Notes

Reaction equation

HRID 131104 reaction equation
C1C2NC3C(=CC=CC=3)SC=2C=CC=1C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H]1CCOC1O)=O)CC(C)C)=O)CC(C)C)=O)CC(C)C)=O.[CH:48]1[C:58]2[CH2:57][CH2:56][C:55]3[CH:59]=[CH:60][CH:61]=[CH:62][C:54]=3[NH:53][C:52]=2[CH:51]=[C:50]([C:63]([NH:65][C@H:66]([C:71]([NH:73][C@H:74]([C:79]([NH:81][C@H:82]2[CH2:86][CH2:85][O:84][CH:83]2[O:87]C)=[O:80])[CH2:75][CH:76]([CH3:78])[CH3:77])=[O:72])[CH2:67][CH:68]([CH3:70])[CH3:69])=[O:64])[CH:49]=1>>[CH:48]1[C:58]2[CH2:57][CH2:56][C:55]3[CH:59]=[CH:60][CH:61]=[CH:62][C:54]=3[NH:53][C:52]=2[CH:51]=[C:50]([C:63]([NH:65][C@H:66]([C:71]([NH:73][C@H:74]([C:79]([NH:81][C@H:82]2[CH2:86][CH2:85][O:84][CH:83]2[OH:87])=[O:80])[CH2:75][CH:76]([CH3:78])[CH3:77])=[O:72])[CH2:67][CH:68]([CH3:70])[CH3:69])=[O:64])[CH:49]=1

Participants

3

Reactant 2

HCID 11216021HCID 11216021, compoundHCID 11467173HCID 11467173, compound

Product 1

HCID 11238189HCID 11238189, compound

Procedure

The experimental protocol is the same as that described for the compound of Example 2 using the compound of Example 61 as starting product. A light beige solid is obtained. Melting point: 142-143° C.

Workup

  1. customA light beige solid is obtained

Sources & evidence

ORD record
ord-c91af0d55b454f6aadf6bab3bad6d3c6
Source dataset
uspto-grants-2008_06
Patent number
US07384933B2

Reaction notes

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