Ammonia → HCID 59732381, compound

HRID 131199Notes

Reaction equation

HRID 131199 reaction equation
[NH3:1].[O:2]1[CH:6]=[CH:5][CH:4]=[C:3]1[C:7]1[C:8]2[S:20][CH:19]=[CH:18][C:9]=2[N:10]=[C:11]([C:13](OCC)=[O:14])[N:12]=1>C(O)C>[O:2]1[CH:6]=[CH:5][CH:4]=[C:3]1[C:7]1[C:8]2[S:20][CH:19]=[CH:18][C:9]=2[N:10]=[C:11]([C:13]([NH2:1])=[O:14])[N:12]=1

Participants

4

Reactant 2

HCID 222AmmoniaHCID 59732298HCID 59732298, compound

Product 1

HCID 59732381HCID 59732381, compoundYield 67%

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

Ammonia gas was bubbled through a hot solution of ethyl 4-(2-furyl)thieno[3,2-d]pyrimidine-2-carboxylate (0.156 g, 0.57 mmol) in ethanol (20 mL) for 3 h then the mixture cooled and the resulting white solid filtered to give the title compound (94 mg, 67%) as a white solid.

Workup

  1. temperaturethe mixture cooled
  2. filtrationthe resulting white solid filtered

Sources & evidence

ORD record
ord-8ea43d3d37c345f491ba748ead3a59aa
Source dataset
uspto-grants-2008_06
Patent number
US07384949B2

Reaction notes

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