HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Hydrazinopyridine → [3,5-Dimethyl-1-(2-pyridyl)-1H-pyrazol-4-yl]methyl-1,2,3,4-tetrahydro-3-methyl-1-(1-methylethyl)-2,4-dioxothieno[2,3-d]pyrimidine-5-carboxylic acid methyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Hydrazinopyridine | HCID 78645 | — |
| Reactant | Methyl 6-(bromomethyl)-1-isopropyl-3-methyl-2,4-dioxo-1,2,3,4-tetrahydrothieno[2,3-d]pyrimidine-5-carboxylate | HCID 68806593 | — |
| Catalyst | Bis(pentane-2,4-dionato-O,O')zinc | HCID 10912358 | — |
| Product | [3,5-Dimethyl-1-(2-pyridyl)-1H-pyrazol-4-yl]methyl-1,2,3,4-tetrahydro-3-methyl-1-(1-methylethyl)-2,4-dioxothieno[2,3-d]pyrimidine-5-carboxylic acid methyl ester | HCID 86603576 | — |
Reaction Steps
Prepared from 6-(bromomethyl)-1,2,3,4-tetrahydro-3-methyl-1-(1-methylethyl)-2,4-dioxothieno[2,3-d]pyrimidine-5-carboxylic acid methyl ester, zinc acetylacetonate hydrate and 2-hydrazinopyridine by the method of example 1 part e) to give the sub-title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07384951B2 |
| Source dataset | uspto-grants-2008_06 |
| ORD ID | ord-ce3fe980149d4162928905f5ebc01ebb |
| Source note | uspto-grants-2008_06 |