反应详情

N-(2-Methoxy-5-nitrobenzyl)acetamide (5 g), with palladium on carbon (1 g) in ethanol (50 ml) was hydrogenated at room temperature under 104 tms. of hydrogen. The reaction was filtered through celite and the ethanol distilled from the filtrate. The residue was recrystallised from benzene to give 3-(acetylaminomethyl)-4-methoxyaniline as pale brown needles. MP; 123-125° C.

1. customwas hydrogenated at room temperature under 104 tms
2. filtrationThe reaction was filtered through celite
3. distillationthe ethanol distilled from the filtrate
4. customThe residue was recrystallised from benzene