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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 131684Generated: October 31, 2026

4-[2-methyl-5-(5-methyl-1,3,4-oxadiazol-2-yl)phenyl]benzoic Acid → HCID 10274115, compound

https://huagongshe.com/reaction/131684

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-[2-methyl-5-(5-methyl-1,3,4-oxadiazol-2-yl)phenyl]benzoic AcidHCID 11220119—
Reactant2-[4-(Aminomethyl)phenyl]ethan-1-olHCID 22601458—
ProductHCID 10274115HCID 10274115—

Reaction Steps

N-[4-(2-Hydroxyethyl)benzyl]-2′-methyl-5′-(5-methyl-1,3,4-oxadiazol-2-yl)-1,1′-biphenyl-4-carboxamide was prepared from 2′-methyl-5′-(5-methyl-1,3,4-oxadiazol-2-yl)-1,1′-biphenyl-4-carboxylic acid and 4-(2-hydroxyethyl)benzylamine using method H. NMR; δH [2H6]—DMSO 9.11,(1H, t), 7.99,(2H, d), 7.89,(1H, dd), 7.76,(1H, d), 7.56-7.51,(3H, m), 7.24,(2H, d), 7.16,(2H, d), 4.62,(1H, t), 4.46,(2H, d), 3.55,(2H, q), 2.69,(2H, t), 2.56,(3H, s), 2.31,(3H, s). LCMS; retention time 3.00 min, MH+ 428.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07384963B2
Source datasetuspto-grants-2008_06
ORD IDord-7a87ecc056a74084926848b94b53f2da
Source noteuspto-grants-2008_06