反应详情

A suspension of methyl 2-(1-(4-fluorophenyl)-1H-indazol-5-yloxy)-2-phenylacetate (137c, 75 mg, 200 μmol) in methanolic NH3 (7 M, 1 ml) was stirred at r.t. overnight to give a clear solution. Then the solvent was removed in vacuo, and the crude product was freeze-dried go give white solid material, 60 mg (83%).

1. customto give a clear solution
2. customThen the solvent was removed in vacuo
3. dry with materialthe crude product was freeze-dried go
4. customgive white solid material, 60 mg (83%)