4-Chlorobenzylamine → HCID 10295475, compound

HRID 131690Notes

Reaction equation

HRID 131690 reaction equation
[CH3:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2[O:9][C:10]([CH3:13])=[N:11][N:12]=2)=[CH:4][C:3]=1[C:14]1[CH:19]=[CH:18][C:17]([C:20](O)=[O:21])=[CH:16][CH:15]=1.[Cl:23][C:24]1[CH:31]=[CH:30][C:27]([CH2:28][NH2:29])=[CH:26][CH:25]=1>>[Cl:23][C:24]1[CH:31]=[CH:30][C:27]([CH2:28][NH:29][C:20]([C:17]2[CH:18]=[CH:19][C:14]([C:3]3[CH:4]=[C:5]([C:8]4[O:9][C:10]([CH3:13])=[N:11][N:12]=4)[CH:6]=[CH:7][C:2]=3[CH3:1])=[CH:15][CH:16]=2)=[O:21])=[CH:26][CH:25]=1

Participants

3

Reactant 2

HCID 660364-ChlorobenzylamineHCID 112201194-[2-methyl-5-(5-methyl-1,3,4-oxadiazol-2-yl)phenyl]benzoic Acid

Product 1

HCID 10295475HCID 10295475, compound

Procedure

N-(4-Chlorobenzyl)-2′-methyl-5′-(5-methyl-1,3,4-oxadiazol-2-yl)-1,1′-biphenyl-4-carboxamide was prepared from 2′-methyl-5′-(5-methyl-1,3,4-oxadiazol-2-yl)-1,1′-biphenyl-4-carboxylic acid and 4-chlorobenzylamine using method N. NMR; δH [2H6]—DMSO 9.17,(1H, t), 7.99,(2H, d), 7.89,(1H, dd), 7.76,(1H, d), 7.56-7.52,(3H, m), 7.41-7.34,(4H, m), 4.49,(2H, d), 2.56,(3H, s), 2.31,(3H, s). LCMS; retention time 3.51 min, MH+ 418/420.

Sources & evidence

ORD record
ord-6d461326d67c45d5873cdc390d0cb1a9
Source dataset
uspto-grants-2008_06
Patent number
US07384963B2

Reaction notes

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