N-(4-AMINO-BENZYL)-ACETAMIDE → HCID 10160461, compound

HRID 131718Notes

Reaction equation

HRID 131718 reaction equation
[CH3:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2[O:9][C:10]([CH3:13])=[N:11][N:12]=2)=[CH:4][C:3]=1[C:14]1[CH:19]=[CH:18][C:17]([C:20](O)=[O:21])=[CH:16][CH:15]=1.[C:23]([NH:26][CH2:27][C:28]1[CH:34]=[CH:33][C:31]([NH2:32])=[CH:30][CH:29]=1)(=[O:25])[CH3:24]>>[C:23]([NH:26][CH2:27][C:28]1[CH:29]=[CH:30][C:31]([NH:32][C:20]([C:17]2[CH:18]=[CH:19][C:14]([C:3]3[CH:4]=[C:5]([C:8]4[O:9][C:10]([CH3:13])=[N:11][N:12]=4)[CH:6]=[CH:7][C:2]=3[CH3:1])=[CH:15][CH:16]=2)=[O:21])=[CH:33][CH:34]=1)(=[O:25])[CH3:24]

Participants

3

Reactant 2

HCID 228286N-(4-AMINO-BENZYL)-ACETAMIDEHCID 112201194-[2-methyl-5-(5-methyl-1,3,4-oxadiazol-2-yl)phenyl]benzoic Acid

Product 1

HCID 10160461HCID 10160461, compound

Procedure

N-[4-(Acetylaminomethyl)phenyl]-2′-methyl-5′-(5-methyl-1,3,4-oxadiazol-2-yl)-1,1′-biphenyl-4-carboxamide was prepared from 2′-methyl-5′-(5-methyl-1,3,4-oxadiazol-2-yl)-1,1′-biphenyl-4-carboxylic acid and 4-(acetylaminomethyl)aniline using method I. LCMS; retention time 2.97 min, MH+ 441.

Sources & evidence

ORD record
ord-bd94998502be4e84a2d51cd85e80b065
Source dataset
uspto-grants-2008_06
Patent number
US07384963B2

Reaction notes

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