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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 131727Generated: November 1, 2026

Iodoethane → N-Ethyl-2'-methyl-5'-(5-methyl-1,3,4-oxadiazol-2-yl)-N-(2-trifluoromethylbenzyl)-1,1'-biphenyl-4-carboxamide

https://huagongshe.com/reaction/131727

Reaction equation

Participants

RoleNameHCIDCharge
ReactantIodoethaneHCID 6340—
ReactantHCID 10114893HCID 10114893—
ProductN-Ethyl-2'-methyl-5'-(5-methyl-1,3,4-oxadiazol-2-yl)-N-(2-trifluoromethylbenzyl)-1,1'-biphenyl-4-carboxamideHCID 10140586—

Reaction Steps

N-Ethyl-2′-methyl-5′-(5-methyl-1,3,4-oxadiazol-2-yl)-N-(2-trifluoromethylbenzyl)-1,1′-biphenyl-4-carboxamide was prepared from 2′-methyl-5′-(5-methyl-1,3,4-oxadiazol-2-yl)-N-(2-trifluoromethylbenzyl)-1,1′-biphenyl-4-carboxamide and iodoethane using method L. NMR; δH [2H6]—DMSO 7.90,(1H. d), 7.78-7.50,(9H, m), 7.38,(1H. b), 4.86-4.68,(2H, m), 3.48-3.32,(2H, b), 2.56,(3H, s), 2.33-2.23,(3H, m), 1.06,(3H, b). LCMS; retention time 3.71 min, MH+ 480.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07384963B2
Source datasetuspto-grants-2008_06
ORD IDord-5c0a3285b03b4c6c83dbe875f008485d
Source noteuspto-grants-2008_06