4-[2-methyl-5-(5-methyl-1,3,4-oxadiazol-2-yl)phenyl]benzoic Acid → HCID 10139792, compound

HRID 131736Notes

Reaction equation

HRID 131736 reaction equation
[CH3:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2[O:9][C:10]([CH3:13])=[N:11][N:12]=2)=[CH:4][C:3]=1[C:14]1[CH:19]=[CH:18][C:17]([C:20](O)=[O:21])=[CH:16][CH:15]=1.[NH2:23][C:24]1[CH:32]=[C:31]2[C:27]([C:28]([CH2:33][N:34]([CH3:36])[CH3:35])=[CH:29][NH:30]2)=[CH:26][CH:25]=1>>[CH3:36][N:34]([CH2:33][C:28]1[C:27]2[C:31](=[CH:32][C:24]([NH:23][C:20]([C:17]3[CH:18]=[CH:19][C:14]([C:3]4[CH:4]=[C:5]([C:8]5[O:9][C:10]([CH3:13])=[N:11][N:12]=5)[CH:6]=[CH:7][C:2]=4[CH3:1])=[CH:15][CH:16]=3)=[O:21])=[CH:25][CH:26]=2)[NH:30][CH:29]=1)[CH3:35]

Participants

3

Reactant 2

HCID 112201194-[2-methyl-5-(5-methyl-1,3,4-oxadiazol-2-yl)phenyl]benzoic AcidHCID 69219361HCID 69219361, compound

Product 1

HCID 10139792HCID 10139792, compound

Procedure

N-[3-(Dimethylaminomethyl)indol-6-yl]-2′-methyl-5′-(5-methyl-1,3,4-oxadiazol-2-yl)-1,1′-biphenyl-4-carboxamide was prepared from 2′-methyl-5′-(5-methyl-1,3,4-oxadiazol-2-yl)-1,1′-biphenyl-4-carboxylic acid and 6amino-3(dimethylaminomethyl)indole using method I. LCMS; retention time 3.16 min, [M-H·]463.

Sources & evidence

ORD record
ord-a78b8ff518ea46adaa3146e6f65fdf0e
Source dataset
uspto-grants-2008_06
Patent number
US07384963B2

Reaction notes

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