4-[2-methyl-5-(5-methyl-1,3,4-oxadiazol-2-yl)phenyl]benzoic Acid → HCID 10118990, compound

HRID 131737Notes

Reaction equation

HRID 131737 reaction equation
[CH3:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2[O:9][C:10]([CH3:13])=[N:11][N:12]=2)=[CH:4][C:3]=1[C:14]1[CH:19]=[CH:18][C:17]([C:20](O)=[O:21])=[CH:16][CH:15]=1.[NH2:23][C:24]1[CH:29]=[CH:28][CH:27]=[CH:26][C:25]=1[C:30]1[CH:35]=[CH:34][C:33]([S:36]([NH2:39])(=[O:38])=[O:37])=[CH:32][CH:31]=1>>[CH3:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2[O:9][C:10]([CH3:13])=[N:11][N:12]=2)=[CH:4][C:3]=1[C:14]1[CH:15]=[CH:16][C:17]([C:20]([NH:23][C:24]2[CH:29]=[CH:28][CH:27]=[CH:26][C:25]=2[C:30]2[CH:35]=[CH:34][C:33]([S:36](=[O:38])(=[O:37])[NH2:39])=[CH:32][CH:31]=2)=[O:21])=[CH:18][CH:19]=1

Participants

3

Reactant 2

HCID 112201194-[2-methyl-5-(5-methyl-1,3,4-oxadiazol-2-yl)phenyl]benzoic AcidHCID 18545753HCID 18545753, compound

Product 1

HCID 10118990HCID 10118990, compound

Procedure

2′-Methyl-5′-(5-methyl-1,3,4-oxadiazol-2-yl)-N-[2-(4-sulphamoylphenyl)phenyl]-1,1′-biphenyl-4-carboxamide was prepared from 2′-methyl-5′-(5-methyl-1,3,4-oxadiazol-2-yl)-1,1′-biphenyl-4-carboxylic acid and 4-(2-aminophenyl)phenylsulphonamide using method I. LCMS; retention time 3.16 min, MH+ 525.

Sources & evidence

ORD record
ord-dccd4080649d4301b54840baf2f3e343
Source dataset
uspto-grants-2008_06
Patent number
US07384963B2

Reaction notes

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