HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Aminothiazole → HCID 10263334, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Aminothiazole | HCID 2155 | — |
| Reactant | 1-Fluoro-2-nitrobenzene | HCID 73895 | — |
| Reactant | HCID 15211606 | HCID 15211606 | — |
| Reactant | HCID 178418616 | HCID 178418616 | — |
| Product | HCID 10263334 | HCID 10263334 | 60% |
| Product | HCID 59732887 | HCID 59732887 | 60% |
Reaction Steps
2-(2-Pyridylsulfanyl)nitrobenzene (0.70 g, 60%) was prepared from 2-mercaptopyridine (0.61 g, 5.5 mmol) and 2-fluoronitrobenzene (0.71 g, 5.0 mmol) following the general procedure A. This compound was reduced to 2-(2-pyridylsulfanyl)aniline (0.37 g, 62%) following general procedure B. N-[2-(2-Pyridylsulfanyl)phenyl]-N′-(thiazol-2-yl)urea (98 mg, 60%) was prepared from 2-(2-pyridylsulfanyl)aniline (101 mg, 0.5 mmol) and 2-aminothiazole (60 mg, 0.6 mmol) following the general procedure D.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07384967B2 |
| Source dataset | uspto-grants-2008_06 |
| ORD ID | ord-10fec773f3364e4e92512c7602f529ff |
| Source note | uspto-grants-2008_06 |