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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 131892Generated: October 31, 2026

Lithium Hydroxide → 3-{2-[3-(2-Cyclopentanecarbonyl-4-methyl-phenyl)-ureido]-thiazol-4-yl}-propionic acid

https://huagongshe.com/reaction/131892

Reaction equation

Participants

RoleNameHCIDCharge
ReactantLithium HydroxideHCID 3939—
Reactant3-(2-[3-(2-Cyclopentanecarbonyl-4-methyl-phenyl)-ureido]-thiazol-4-yl)-propionic acid ethyl esterHCID 59733066—
Product3-{2-[3-(2-Cyclopentanecarbonyl-4-methyl-phenyl)-ureido]-thiazol-4-yl}-propionic acidHCID 5973307793.4%

Reaction Steps

3-{2-[3-(2-Cyclopentanecarbonyl-4-methyl-phenyl)-ureido]-thiazol-4-yl}-propionic acid (15 mg, 88%) was prepared from 3-{2-[3-(2-Cyclopentanecarbonyl-4-methyl-phenyl)-ureido]-thiazol-4-yl}-propionic acid ethyl ester (0.03 g, 0.04 mmol) and 2.5M LiOH (20 ΞL) following the general procedure J.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07384967B2
Source datasetuspto-grants-2008_06
ORD IDord-7d15a389a0ce4a1a81b5089b34ef5bfa
Source noteuspto-grants-2008_06