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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 131913Generated: October 28, 2026

1-(5-Bromothiazol-2-yl)-3-(2-cyclopentanecarbonyl-4-methyl-phenyl)-urea → HCID 59733150, compound

https://huagongshe.com/reaction/131913

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-(5-Bromothiazol-2-yl)-3-(2-cyclopentanecarbonyl-4-methyl-phenyl)-ureaHCID 59732797—
ReactantHCID 178498116HCID 178498116—
ProductHCID 59733150HCID 5973315025%

Reaction Steps

2-{2-[3-(2-Cyclopentanecarbonyl-4-methyl-phenyl)-ureido]-thiazol-5-ylsulfanyl}-nicotinic acid methyl ester (124 mg, 25%) was prepared from 1-(5-bromo-thiazol-2-yl)-3-(2-cyclopentanecarbonyl-4-methyl-phenyl)-urea (408 mg, 1 mmol) and 2-mercapto-nicotinic acid methyl ester (340 mg, 2 mmol) following the general procedure Q.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07384967B2
Source datasetuspto-grants-2008_06
ORD IDord-9a257f9e8a614a319acf8f423cf23c74
Source noteuspto-grants-2008_06