HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Aminothiazole → HCID 59732765, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Aminothiazole | HCID 2155 | — |
| Reactant | Isobutyl mercaptan | HCID 10558 | — |
| Reactant | Benzene, 2-fluoro-4-methyl-1-nitro- | HCID 67966 | — |
| Reactant | HCID 66999170 | HCID 66999170 | — |
| Product | HCID 59732765 | HCID 59732765 | 68% |
| Product | HCID 66998659 | HCID 66998659 | 67% |
Reaction Steps
3-(Isobutylsulfanyl)-4-nitrotoluene (0.75 g, 67%) was prepared from 2-methyl-propanethiol and 3-fluoro-4-nitrotoluene (0.77 g, 5.0 mmol) following the general procedure A. This was reduced to 2-isobutylsulfanyl-4-methyl-aniline (0.46 g, 63%) following general procedure B. 1-(2-Isobutylsulfanyl-4-methyl-phenyl)-3-thiazol-2-yl-urea (218 mg, 68%) was prepared from 2-isobutylsulfanyl-4-methyl-aniline (195 mg, 1.0 mmol) and 2-aminothiazole (100 mg, 1.0 mmol) following the general procedure D.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07384967B2 |
| Source dataset | uspto-grants-2008_06 |
| ORD ID | ord-05fcd67f24c14ff7970d2b85df9e0d96 |
| Source note | uspto-grants-2008_06 |