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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 131967Generated: October 26, 2026

Ethyl Acetate → {2-[3-(2-Cyclopentanesulfonyl-4-methyl-phenyl)-ureido]-thiazol-4-yl}-acetic acid ethyl ester

https://huagongshe.com/reaction/131967

Reaction equation

Participants

RoleNameHCIDCharge
ReactantEthyl AcetateHCID 8857—
Reactant4-Thiazoleacetic acid, 2-amino-, ethyl esterHCID 104454—
Reactant2-Cyclopentanesulfonyl-4-methyl-phenylamineHCID 66998974—
Product{2-[3-(2-Cyclopentanesulfonyl-4-methyl-phenyl)-ureido]-thiazol-4-yl}-acetic acid ethyl esterHCID 59733115—

Reaction Steps

{2-[3-(2-Cyclopentanesulfonyl-4-methyl-phenyl)-ureido]-thiazol-4-yl{-acetic acid ethyl ester (305 mg, 68%) was prepared from 2-cyclopentanesulfonyl-4-methyl-aniline (239 mg, 1.0 mmol) and ethyl 2-amino-4-thiazolylacetate (186 mg, 1.0 mmol) following the general procedure D.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07384967B2
Source datasetuspto-grants-2008_06
ORD IDord-b8a9fb8afdde45e1b1d3ad151b178db9
Source noteuspto-grants-2008_06