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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 13197Generated: October 25, 2026

3-Isoxazolecarboxylic acid → HCID 59339803, compound

https://huagongshe.com/reaction/13197

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-Isoxazolecarboxylic acidHCID 11286453—
Reactant(1R,2S)-1-(1-(4-fluorophenyl)indazol-5-yloxy)-1-(3-methoxyphenyl)propan-2-amineHCID 59339733—
ProductHCID 59339803HCID 59339803—

Reaction Steps

Prepared as described in Example 269 from (1R,2S)-1-(1-(4-fluorophenyl)-1H-indazol-5yloxy)-1-(3-methoxyphenyl)propan-2-amine (6a, 50 mg, 0.13 mmol) and isoxazole-3-carboxylic acid (17 mg, 0.15 mmol).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07728030B2
Source datasetuspto-grants-2010_06
ORD IDord-31d0aafe3626463bbac9032e8fb89a22
Source noteuspto-grants-2010_06