HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1322305Generated: October 30, 2026
Morpholine → 4-(4-Trifluoromethylphenyl)morpholine
https://huagongshe.com/reaction/1322305
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Morpholine | HCID 8083 | — |
| Reactant | Benzene, 1-bromo-4-(trifluoromethyl)- | HCID 67872 | — |
| Reagent | CID 14794698 | HCID 14794698 | — |
| Catalyst | Di-tert-butyl(2',4',6'-tris(propan-2-yl)-(1,1'-biphenyl)-2-yl)phosphane | HCID 11618717 | — |
| Catalyst | HCID 178476681 | HCID 178476681 | — |
| Solvent | Dimethyl Sulfoxide | HCID 679 | — |
| Solvent | M-Xylene | HCID 7929 | — |
| Solvent | HCID 178504073 | HCID 178504073 | — |
| Product | Caffeine | HCID 2519 | — |
| Product | 4-(4-Trifluoromethylphenyl)morpholine | HCID 10933310 | 0.32% |
| Product | 4-(3-(Trifluoromethyl)phenyl)morpholine | HCID 15420299 | 0% |
Provenance & Evidence
| DOI | 10.1021/jacs.6c05959 |
|---|
| Source dataset | High-throughput exploration of 50,688 Pd-, Ni- and Cu-catalysed C–N coupling reactions |
|---|
| ORD ID | ord-f0c1a0b0e64940efb81ba23e0823082e |
|---|
| Source note | High-throughput exploration of 50,688 Pd-, Ni- and Cu-catalysed C–N coupling reactions |
|---|
