HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 13225Generated: October 30, 2026
t-Butyl (R)-1-hydroxy-1-(3-methoxy-4-(methylthio)phenyl)propan-2-ylcarbamate → HCID 66812852, compound
https://huagongshe.com/reaction/13225
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | t-Butyl (R)-1-hydroxy-1-(3-methoxy-4-(methylthio)phenyl)propan-2-ylcarbamate | HCID 86623011 | — |
| Solvent | Ethyl Acetate | HCID 8857 | — |
| Product | HCID 66812852 | HCID 66812852 | — |
Reaction Steps
t-Butyl (R)-1-hydroxy-1-(3-methoxy-4-(methylthio)phenyl)propan-2-ylcarbamate (308c, 44 μg, 130 μmol) was dissolved in a solution of HC in ethyl acetate (1M, 5 mL) and stirred at 60° C. for 2 h. The solvent was evaporated, and the diastereomers were separated by HPLC (XBridge column). The subtitle compound is the first eluted product, 17 mg (55%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US07728030B2 |
|---|
| Source dataset | uspto-grants-2010_06 |
|---|
| ORD ID | ord-763b9194fd804b829a1dc772f17f5c7c |
|---|
| Source note | uspto-grants-2010_06 |
|---|
