Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 13235Generated: October 26, 2026

2-Hydroxy-N,N-dimethylbenzamide → 5-(2-Dimethylcarbamoyl-phenoxy)-6-(4-methanesulfonyl-phenoxy)-2-pyridin-2-yl-1H-benzimidazole

https://huagongshe.com/reaction/13235

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Hydroxy-N,N-dimethylbenzamideHCID 74500—
Reactant5-(2-Ethoxycarbonyl-phenoxy)-6-(4-methanesulfonyl-phenoxy)-2-pyridin-2-yl-1H-benzimidazoleHCID 23145140—
Product5-(2-Dimethylcarbamoyl-phenoxy)-6-(4-methanesulfonyl-phenoxy)-2-pyridin-2-yl-1H-benzimidazoleHCID 23145352—

Reaction Steps

The entitled compound was obtained in the same method as in Example 14 or in accordance with the method or by combining it with an ordinary method but using 4-fluoro-5-(4-methanesulfonyl-phenoxy)-2-nitro-phenylamine obtained in Example 14 and 2-hydroxybenzoic acid dimethylamide in order.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07728025B2
Source datasetuspto-grants-2010_06
ORD IDord-add36451338c4ee9a2bb43c5f598956f
Source noteuspto-grants-2010_06