3-(2-Methoxyphenoxy)-2-nitro-5-(pyridin-3-yloxy)-aniline → 3-(2-Methoxyphenoxy)-5-(pyridin-3-yloxy)-benzene-1,2-diamine

Participants

Reaction Steps

1 g of 20% palladium hydroxide-carbon catalyst was added to a methanol (20 ml) solution of 1.33 g of 3-(2-methoxyphenoxy)-2-nitro-5-(pyridin-3-yloxy)-aniline, and the reaction liquid was stirred for 4 hours in a hydrogen atmosphere. The catalyst was removed through filtration, the solvent was evaporated away under reduced pressure, and the resulting residue was purified through silica gel column chromatography (developing solvent: hexane/ethyl acetate=1/2 to ethyl acetate) to obtain the entitled compound as a pale orange oily substance.

Provenance & Evidence