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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 132496Generated: October 31, 2026

HCID 59731929, compound → HCID 11977529, compound

https://huagongshe.com/reaction/132496

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 59731929HCID 59731929—
Reactant4-Chloro-9-(2,2-dimethyl-propyl)-7-(R)-{2-oxo-2-[4-(2-oxo-1,4-dihydro-2H-quinazolin-3-yl)-piperidin-1-yl]-ethyl}-6,7,9,10-tetrahydro-3H-2,3,9-triaza-cyclohepta[e]inden-8-oneHCID 68826479—
ProductHCID 11977529HCID 1197752964%

Reaction Steps

3-(piperidin-4-yl)-1,8-naphthyridin-2(1H)-one (57 mg, 0.19 mmol) and [4-chloro-9-(2,2-dimethyl-propyl)-8-oxo-3,6,7,8,9,10-hexahydro-2,3,9-triaza-(S)-cyclohepta[e]inden-7-yl]acetic acid (60 mg, 0.16 mmol) were combined in a manner analogous to the preparation of 4-Chloro-9-(2,2-dimethyl-propyl)-7-(R)-{2-oxo-2-[4-(2-oxo-1,4-dihydro-2H-quinazolin-3-yl)-piperidin-1-yl]-ethyl}-6,7,9,10-tetrahydro-3H-2,3,9-triaza-cyclohepta[e]inden-8-one. Title compound was obtained as white solid in 64% yield. High resolution MS m/e (M+H)+=575.2538.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07384931B2
Source datasetuspto-grants-2008_06
ORD IDord-d2fe4bedd0364b01a660560c5070fd2b
Source noteuspto-grants-2008_06