Benzoyl chloride → HCID 66899465, compound

HRID 132724Notes

Reaction equation

[C:1](Cl)(=[O:8])[C:2]1[CH:7]=CC=CC=1.[C:10](Cl)(=[O:13])[CH2:11][CH3:12].[C:15]1([CH:21]([OH:32])[CH:22](C)[CH:23]([C:25]2[CH:30]=[CH:29][CH:28]=[CH:27][CH:26]=2)[OH:24])[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=1.C1(C(O)CC(C2C=CC=CC=2)O)C=CC=CC=1>>[C:10]([O:32][CH:21]([C:15]1[CH:16]=[CH:17][CH:18]=[CH:19][CH:20]=1)[CH2:22][CH:23]([C:25]1[CH:26]=[CH:27][CH:28]=[CH:29][CH:30]=1)[O:24][C:1](=[O:8])[CH2:2][CH3:7])(=[O:13])[CH2:11][CH3:12]

Participants

Reactant 4

HCID 7412Benzoyl chloride

HCID 62324Propionyl chloride

HCID 2317721,3-Diphenylpropane-1,3-diol

HCID 10800210HCID 10800210, compound

Product 1

HCID 66899465HCID 66899465, compound

Procedure

Synthetic procedure was identical with that described in synthetic example 42(3), except that benzoyl chloride was replaced by propionyl chloride, and 1,3-diphenyl-2-methyl-1,3-propandiol was replaced by 1,3-diphenyl-1,3-propandiol. 1HNMR: δ (ppm) 7.13-7.36(10H, ArH), 5.76(2H, CH), 2.5(4H, CH2), 2.11(2H, CH2), 1.1(6H, CH3)

Sources & evidence

ORD record: ord-eb0416494144464dbf52f47b11fa0f6a
Source dataset: uspto-grants-2008_06
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07388061B2

Reaction notes

Loading…