Pyridine → HCID 23126010, compound

Participants

Reaction Steps

To 7.5 g (0.04 mol) 2,2-diisobutyl-1,3-propandiol was added 50 ml tetrahydrofuran, then added 9.7 ml (0.12 mol) pyridine with stirring. To the resulting homogenous mixture was slowly added 11.6 ml (0.1 mol) benzoyl chloride. The mixture was stirred at room temperature for 1 hour, and heated refluxing for 5 hours. Upon completing the reaction, 40 ml water was added to dissolve the resulting salt. The mixture was extracted with ethyl acetate. The organic phase was separated, washed with saturated saline for two times, and dried over anhydrous sodium sulfate. The solvent was removed. Distillation under reduced pressure gave 2,2-diisobutyl-1,3-propandiol dibenzoate as a pale yellow liquid, the yield was 93%.

Provenance & Evidence