HRID132846

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID521305

1-Chloroethyl carbonochloridate

C3H4Cl2O2

HCID57770916

6-Benzyl-2-(trifluoromethyl)-5,6,7,8-tetrahydro-1,6-naphthyridine

C16H15F3N2

PRODUCTS

生成物

HCID57445256

2-(Trifluoromethyl)-5,6,7,8-tetrahydro-1,6-naphthyridine--hydrogen chloride (1/1)

C9H10ClF3N2

AUXILIARIES

试剂、催化剂与溶剂

溶剂HCID3283

Diethyl Ether

C4H10O

PROCEDURE

实验过程

Treatment of the intermediate from Step A above with 1-chloroethyl chloroformate as described for Intermediate 20, Step C afforded the crude title compound. Trituration with ether provided the title compound as a pale orange powder. LC/MS 203.1 (M+1).

WORKUP

后处理

customafforded the crude title compound