HuagongsheHuagongshe Chemistry Print Report · For research reference only
Trifluoroacetic acid → 2-Methyl-5,6,7,8-tetrahydropyrido[4,3-d]pyrimidine, trifluoroacetate salt
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Trifluoroacetic acid | HCID 6422 | — |
| Reactant | tert-Butyl 2-methyl-7,8-dihydropyrido[4,3-d]pyrimidine-6(5H)-carboxylate | HCID 69223447 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | 2-Methyl-5,6,7,8-tetrahydropyrido[4,3-d]pyrimidine, trifluoroacetate salt | HCID 131726931 | — |
Reaction Steps
Reaction of the product from Step A above with trifluoroacetic acid in dichloromethane according to the procedure outlined for Intermediate 28, Step C afforded the title compound as a light orange powder. LC/MS 150.1 (M+1).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07388019B2 |
| Source dataset | uspto-grants-2008_06 |
| ORD ID | ord-6e4a4110fd734a84b43ed6b6d96031e2 |
| Source note | uspto-grants-2008_06 |