Water → HCID 21106192, compound

HRID 132972Notes

Reaction equation

HRID 132972 reaction equation
[I-].[CH2:2]([N+:4]1([CH2:15][CH3:16])[CH:13]2[CH:8]([CH2:9][CH2:10][CH2:11][CH2:12]2)[CH2:7][CH2:6][CH:5]1[CH3:14])[CH3:3].[OH2:17]>>[OH-:17].[CH2:15]([N+:4]1([CH2:2][CH3:3])[CH:13]2[CH:8]([CH2:9][CH2:10][CH2:11][CH2:12]2)[CH2:7][CH2:6][CH:5]1[CH3:14])[CH3:16].[CH2:15]([N+:4]1([CH2:2][CH3:3])[CH:13]2[CH:8]([CH2:9][CH2:10][CH2:11][CH2:12]2)[CH2:7][CH2:6][CH:5]1[CH3:14])[CH3:16]

Participants

4

Reactant 2

HCID 962WaterHCID 21106197HCID 21106197, compound

Product 2

HCID 21106192HCID 21106192, compoundHCID 21106196HCID 21106196, compound

Procedure

The hydroxide version of N,N-diethyl-2-methyldecahydro-quinolinium cation was prepared by ion exchange as described in the procedure below. To a solution of 20 gm (0.06 mol) of N,N-diethyl-2-methyldecahydro-quinolinium iodide in 80 ml water, 80 gm of OH-ion exchange resin (BIO RAD® AGI-X8) was added, and the resulting mixture was allowed to gently stir at room temperature for few hours. The mixture was filtered and the ion exchange resin was rinsed with additional 30 ml water (to ensure removing all the cations from the resin). The rinse and the original filtrate were combined and titration analysis on a small sample of the filtrate with 0.1N HCl indicated a 0.5M OH ions concentration (0.055 mol cations). Scheme 1 below depicts the synthesis of the templating agent.

Workup

  1. filtrationThe mixture was filtered
  2. washthe ion exchange resin was rinsed with additional 30 ml water (
  3. customto ensure removing all the cations from the resin)
  4. washThe rinse
  5. concentrationa 0.5M OH ions concentration (0.055 mol cations)
  6. customthe synthesis of the templating agent

Sources & evidence

ORD record
ord-4e86f4d768b245b1ac9ecb2db4625f37
Source dataset
uspto-grants-2008_06
Patent number
US07390395B2

Reaction notes

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