Methyl pyrazine-2-carboximidate → HCID 23145711, compound

HRID 13302Notes

Reaction equation

HRID 13302 reaction equation
[F:1][C:2]([F:37])([F:36])[C:3]1[CH:35]=[CH:34][CH:33]=[CH:32][C:4]=1[O:5][C:6]1[C:20]([O:21][C:22]2[CH:23]=[N:24][C:25]([S:28]([CH3:31])(=[O:30])=[O:29])=[CH:26][CH:27]=2)=[CH:19][C:9]2[NH:10][C:11]([C:13]3[CH:18]=C[CH:16]=[CH:15][N:14]=3)=[N:12][C:8]=2[CH:7]=1.COC(C1C=NC=CN=1)=[NH:41]>>[F:37][C:2]([F:1])([F:36])[C:3]1[CH:35]=[CH:34][CH:33]=[CH:32][C:4]=1[O:5][C:6]1[C:20]([O:21][C:22]2[CH:23]=[N:24][C:25]([S:28]([CH3:31])(=[O:30])=[O:29])=[CH:26][CH:27]=2)=[CH:19][C:9]2[NH:10][C:11]([C:13]3[CH:18]=[N:41][CH:16]=[CH:15][N:14]=3)=[N:12][C:8]=2[CH:7]=1

Participants

3

Reactant 2

HCID 470894Methyl pyrazine-2-carboximidateHCID 231451315-(2-Trifluoromethyl-phenoxy)-2-pyridin-2-yl-6-(6-methanesulfonyl-pyridin-3-yloxy)-1H-benzimidazole

Product 1

HCID 23145711HCID 23145711, compound

Procedure

The entitled compound was obtained as a yellow solid in the same method as in Example 205 or in accordance with the method or by combining it with an ordinary method but using 4-(2-trifluoromethyl-phenoxy)-5-(6-methanesulfonyl-pyridin-3-yloxy)-benzene-1,2-diamine obtained in Example 206, and methylpyrazin-2-imidate.

Workup

  1. customThe entitled compound was obtained as a yellow solid in the same method as in Example 205 or in accordance with the method

Sources & evidence

ORD record
ord-1ee03722fc2f4fc29329f505d5006ca9
Source dataset
uspto-grants-2010_06
Patent number
US07728025B2

Reaction notes

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