HuagongsheHuagongshe Chemistry Print Report · For research reference only
1H-Pyrazole-3-carbaldehyde → 5-(2-Cyanopyridin-3-yloxy)-2-(1H-pyrazol-3-yl)-6-(6-methanesulfonyl-pyridin-3-yloxy)-1H-benzimidazole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1H-Pyrazole-3-carbaldehyde | HCID 12218383 | — |
| Reactant | 5-(2-cyanopyridin-3-yloxy)-6-(6-methanesulfonyl-pyridin-3-yloxy)-2-pyridin-2-yl-1H-benzimidazole | HCID 23145695 | — |
| Product | 5-(2-Cyanopyridin-3-yloxy)-2-(1H-pyrazol-3-yl)-6-(6-methanesulfonyl-pyridin-3-yloxy)-1H-benzimidazole | HCID 178504807 | — |
Reaction Steps
The entitled compound was obtained as a colorless solid in the same method as in Example 202 or in accordance with the method or by combining it with an ordinary method but using 4-(2-cyanopyridin-3-yloxy)-5-(6-methanesulfonyl-pyridin-3-yloxy)-benzene-1,2-diamine obtained in Example 218 (step 3) and 1H-pyrazole-3-carboxaldehyde.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07728025B2 |
| Source dataset | uspto-grants-2010_06 |
| ORD ID | ord-e2d9d0f81bdd4219a823d248be209895 |
| Source note | uspto-grants-2010_06 |