HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyl pyrazine-2-carboximidate → 5-(2-Fluoro-phenoxy)-2-pyrazin-2-yl-6-(6-ethanesulfonyl-pyridin-3-yloxy)-1H-benzimidazole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyl pyrazine-2-carboximidate | HCID 470894 | — |
| Reactant | 5-(2-Fluoro-phenoxy)-2-pyridin-2-yl-6-(6-ethanesulfonyl-pyridin-3-yloxy)-1H-benzimidazole | HCID 11397704 | — |
| Product | 5-(2-Fluoro-phenoxy)-2-pyrazin-2-yl-6-(6-ethanesulfonyl-pyridin-3-yloxy)-1H-benzimidazole | HCID 23145437 | — |
Reaction Steps
The entitled compound was obtained as a brown solid in the same method as in Example 205 or in accordance with the method or by combining it with an ordinary method but using 4-(2-fluoro-phenoxy)-5-(6-ethanesulfonyl-pyridin-3-yloxy)-benzene-1,2-diamine obtained in Example 223 and methylpyrazin-2-imidate.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07728025B2 |
| Source dataset | uspto-grants-2010_06 |
| ORD ID | ord-d19c82f9ec2a49289d38b2d29f4086c9 |
| Source note | uspto-grants-2010_06 |