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3-Pyridineacetic acid, hydrochloride (1:1) → N-[(3pyridyl)acetyl]-D,L-alanine iso-butyl ester
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 3-Pyridineacetic acid, hydrochloride (1:1) | HCID 2723724 | — |
| 反応物 | 2-Methylpropyl 2-aminopropanoate hydrochloride | HCID 86200109 | — |
| 生成物 | N-[(3pyridyl)acetyl]-D,L-alanine iso-butyl ester | HCID 22492127 | — |
反応手順
Following General Procedure BF and using 3-pyridylacetic acid hydrochloride (Aldrich) and D,L-alanine iso-butyl ester hydrochloride (from Example BB above), the title compound was prepared as a solid having a melting point of 62-64° C. The reaction was monitored by tlc on silica gel (Rf=0.48 10% methanol/dichloromethane) and purification was by silica gel chromatography.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US07390801B2 |
| 出典データセット | uspto-grants-2008_06 |
| ORD ID | ord-6e9b87ccc9ae4aecac703970ee4eb8ad |
| 出典メモ | uspto-grants-2008_06 |