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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 133375Generated: October 27, 2026

3-(Trifluoromethyl)benzeneacetic acid → 2-[(3-trifluoromethylphenyl)acetamido]butyric Acid Iso-butyl Ester

https://huagongshe.com/reaction/133375

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-(Trifluoromethyl)benzeneacetic acidHCID 67695—
ReactantIsobutyl 2-aminobutyrateHCID 13743360—
Product2-[(3-trifluoromethylphenyl)acetamido]butyric Acid Iso-butyl EsterHCID 15481772—

Reaction Steps

Following General Procedure BI above and using 3-trifluoromethyl-phenylacetic acid (Aldrich) and iso-butyl 2-aminobutyrate (prepared following General Procedure BJ above), the title compound was prepared. The reaction was monitored by tlc on silica gel and purification was by filtration as described in the general procedure.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07390801B2
Source datasetuspto-grants-2008_06
ORD IDord-9cfde4f414fe419abf5e735f51974a1a
Source noteuspto-grants-2008_06