HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1333803Generated: November 1, 2026
3-Bromopyridine → 3-(4-Phenyl-1-piperidinyl)pyridine
https://huagongshe.com/reaction/1333803
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | 3-Bromopyridine | HCID 12286 | — |
| Reactant | 4-Phenylpiperidine | HCID 69873 | — |
| Reagent | 2-tert-Butyl-1,1,3,3-tetramethylguanidine | HCID 3571581 | — |
| Catalyst | Copper(1+) iodide; Copper(I) iodide; Cuprous iodide; Cuprous iodide (CuI) | HCID 24350 | — |
| Catalyst | (1S,2S)-(-)-1,2-Diaminocyclohexane-N,N'-bis(2'-diphenylphosphinobenzoyl) | HCID 10963521 | — |
| Solvent | Dimethyl Sulfoxide | HCID 679 | — |
| Product | Caffeine | HCID 2519 | — |
| Product | 3-(4-Phenyl-1-piperidinyl)pyridine | HCID 122380223 | 0% |
| Product | 4-(4-Phenylpiperidin-1-yl)pyridine | HCID 139888337 | 0% |
Provenance & Evidence
| DOI | 10.1021/jacs.6c05959 |
|---|
| Source dataset | High-throughput exploration of 50,688 Pd-, Ni- and Cu-catalysed C–N coupling reactions |
|---|
| ORD ID | ord-ddff218e0acf4731a58f50c0aae46a4f |
|---|
| Source note | High-throughput exploration of 50,688 Pd-, Ni- and Cu-catalysed C–N coupling reactions |
|---|
