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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 133383Generated: October 25, 2026

2-(3-Methyl-1,2-oxazol-5-yl)acetic acid → N-[(3-methylisoxazol-5yl)acetyl]alanine Iso-butyl Ester

https://huagongshe.com/reaction/133383

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-(3-Methyl-1,2-oxazol-5-yl)acetic acidHCID 4195532—
Reactant2-methylpropyl (2S)-2-aminopropanoateHCID 13743556—
ProductN-[(3-methylisoxazol-5yl)acetyl]alanine Iso-butyl EsterHCID 15481782—

Reaction Steps

Following General Procedure BI above, and using (3-methyl-isoxazol-5-yl)acetic acid (CAS#19668-85-0) and alanine iso-butyl ester (prepared following General Procedure BJ above), the title compound was prepared. The reaction was monitored by tlc on silica gel and purification was by filtration as described in the general procedure.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07390801B2
Source datasetuspto-grants-2008_06
ORD IDord-2d40030507104c0b8acce856b77d8f1e
Source noteuspto-grants-2008_06