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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 133385Generated: October 25, 2026

m-Tolylacetic acid → N-[(3-methylphenyl)acetyl]alanine Iso-butyl Ester

https://huagongshe.com/reaction/133385

Reaction equation

Participants

RoleNameHCIDCharge
Reactantm-Tolylacetic acidHCID 12121—
Reactant2-methylpropyl (2S)-2-aminopropanoateHCID 13743556—
ProductN-[(3-methylphenyl)acetyl]alanine Iso-butyl EsterHCID 53803690—

Reaction Steps

Following General Procedure BI above, and using 3-methylphenylacetic acid (Aldrich) and alanine iso-butyl ester (prepared following General Procedure BJ above), the title compound was prepared. The reaction was monitored by tlc on silica gel and purification was by filtration as described in the general procedure.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07390801B2
Source datasetuspto-grants-2008_06
ORD IDord-e49bb37729d7445db35f1a373922cad0
Source noteuspto-grants-2008_06