HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1334721Generated: October 28, 2026
3-Bromopyridine → 3-(4-Phenyl-1-piperidinyl)pyridine
https://huagongshe.com/reaction/1334721
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | 3-Bromopyridine | HCID 12286 | — |
| Reactant | 4-Phenylpiperidine | HCID 69873 | — |
| Reagent | 7-Methyl-1,5,7-triazabicyclo[4.4.0]dec-5-ene | HCID 123583 | — |
| Catalyst | 2-Di-tert-butylphosphino-2'-(N,N-dimethylamino)biphenyl | HCID 2734936 | — |
| Catalyst | HCID 178440864 | HCID 178440864 | — |
| Solvent | Dimethyl Sulfoxide | HCID 679 | — |
| Product | Caffeine | HCID 2519 | — |
| Product | 3-(4-Phenyl-1-piperidinyl)pyridine | HCID 122380223 | 0.792% |
| Product | 4-(4-Phenylpiperidin-1-yl)pyridine | HCID 139888337 | 0% |
Provenance & Evidence
| DOI | 10.1021/jacs.6c05959 |
|---|
| Source dataset | High-throughput exploration of 50,688 Pd-, Ni- and Cu-catalysed C–N coupling reactions |
|---|
| ORD ID | ord-f75cb94ef8dc4c4a80ee89b01b606416 |
|---|
| Source note | High-throughput exploration of 50,688 Pd-, Ni- and Cu-catalysed C–N coupling reactions |
|---|
