HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → 2,4-dibromo-3-(N,N-di-n-propylaminocarbonylmethoxy)benzoic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | ethyl 2,4-dibromo-3-(N,N-di-n-propylaminocarbonylmethoxy)benzoate | HCID 12115355 | — |
| Solvent | Water | HCID 962 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | 2,4-dibromo-3-(N,N-di-n-propylaminocarbonylmethoxy)benzoic acid | HCID 12115356 | — |
Reaction Steps
1.24 g (2.70 mmol) of ethyl 2,4-dibromo-3-(N,N-di-n-propylaminocarbonylmethoxy)benzoate were dissolved in 10 ml of THF and 10 ml of H2O, and 0.117 g of NaOH was added. After stirring at RT for 12 h the mixture was admixed with 6 N HCl and extracted with CH2Cl2. Drying of the organic phase over Na2SO4 gave 2,4-dibromo-3-(N,N-di-n-propylaminocarbonylmethoxy)benzoic acid as a viscous colorless oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07390827B2 |
| Source dataset | uspto-grants-2008_06 |
| ORD ID | ord-2fac132d2f5e4b9b897344f5d8d29eb1 |
| Source note | uspto-grants-2008_06 |