HRID13369

反应详情

EQUATION

反应方程式

REACTANTS

反应物

结构：CCOC(=O)c1ccccc1Oc1cc2nc(-c3ccccn3)[nH]c2cc1Oc1ccc(S(C)(=O)=O)cc1

HCID23145140

未命名化合物

HCID86619210

未命名化合物

PRODUCTS

生成物

结构：CON(C)C(=O)[C@H]1CCCN1c1cc2[nH]c(-c3ccccn3)nc2cc1Oc1ccc(S(C)(=O)=O)cc1

HCID86619209

未命名化合物

PROCEDURE

实验过程

The entitled compound was obtained in the same method as in Example 15 or in accordance with the method or by combining it with an ordinary method but using 5-fluoro-4-(4-methanesulfonyl-phenoxy)-2-nitro-phenylamine obtained in Example 14, and (R)—N-methoxy-N-methylprolinamide.

WORKUP

后处理

customThe entitled compound was obtained in the same method as in Example 15 or in accordance with the method

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-d23f453932ce467ab722914a811b2947
来源数据集: uspto-grants-2010_06
DOI: 10.6084/m9.figshare.5104873.v1
专利: US07728025B2
来源说明: uspto-grants-2010_06

反应 SMILES

C(OC(C1C=CC=CC=1O[C:9]1[C:23]([O:24][C:25]2[CH:30]=[CH:29][C:28]([S:31]([CH3:34])(=[O:33])=[O:32])=[CH:27][CH:26]=2)=[CH:22][C:12]2[NH:13][C:14]([C:16]3[CH:21]=[CH:20][CH:19]=[CH:18][N:17]=3)=[N:15][C:11]=2[CH:10]=1)=O)C.[CH3:39][O:40][N:41]([CH3:49])[C:42](=[O:48])[C@H:43]1[CH2:47][CH2:46][CH2:45][NH:44]1>>[CH3:39][O:40][N:41]([CH3:49])[C:42]([C@H:43]1[CH2:47][CH2:46][CH2:45][N:44]1[C:9]1[C:23]([O:24][C:25]2[CH:30]=[CH:29][C:28]([S:31]([CH3:34])(=[O:33])=[O:32])=[CH:27][CH:26]=2)=[CH:22][C:12]2[N:13]=[C:14]([C:16]3[CH:21]=[CH:20][CH:19]=[CH:18][N:17]=3)[NH:15][C:11]=2[CH:10]=1)=[O:48]