Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
4-Hydroxybenzoic Acid → 4-Hydroxy-3-iodobenzoic acid (2IPCOOH)
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 4-Hydroxybenzoic Acid | HCID 135 | — |
| 반응물 | Sulfuric Acid | HCID 1118 | — |
| 반응물 | Sodium Iodide | HCID 5238 | — |
| 반응물 | Sodium Hydroxide | HCID 14798 | — |
| 반응물 | Sodium Hypochlorite | HCID 23665760 | — |
| 용매 | Water | HCID 962 | — |
| 생성물 | 4-Hydroxy-3-iodobenzoic acid (2IPCOOH) | HCID 449473 | — |
반응 단계
30 g of 4-hydroxybenzoic acid are placed in 780 ml of water containing 18 g of sodium hydroxide, 49.5 g of sodium iodide are added, 675 ml of 3.5% sodium hypochlorite solution are run in slowly and the mixture is left with stirring at AT for 13 hours. 60 ml of concentrated H2SO4 are added and then, after cooling, the precipitate formed is filtered off and washed with water. This gives 32.46 g of the expected compound, m.p.=163° C.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07390924B2 |
| 출처 데이터셋 | uspto-grants-2008_06 |
| ORD ID | ord-f4bd56211cd14a3fb5d2d390152a6732 |
| 출처 메모 | uspto-grants-2008_06 |