Benzylamine → HCID 21083189, compound

HRID 133711Notes

Reaction equation

HRID 133711 reaction equation
[CH2:1]([NH2:8])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[OH:9][CH:10]([CH:13]([OH:20])[CH:14]([OH:19])[CH:15]([OH:18])[CH2:16][OH:17])[CH2:11][NH-:12].[O:21]([C:31]1[CH:39]=[CH:38][C:34]([C:35]([OH:37])=O)=[CH:33][CH:32]=1)[C:22]1[CH:30]=[CH:29][C:25]([C:26]([OH:28])=[O:27])=[CH:24][CH:23]=1>>[OH:9][CH:10]([CH:13]([OH:20])[CH:14]([OH:19])[CH:15]([OH:18])[CH2:16][OH:17])[CH2:11][NH-:12].[OH:9][CH:10]([C:11]1[CH:6]=[CH:7][CH:2]=[CH:3][CH:4]=1)[CH2:13][CH2:14][CH:15]1[CH:1]([C:2]2[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=2)[N:8]([C:5]2[CH:6]=[CH:7][C:2]([CH2:1][NH:8][C:35]([C:34]3[CH:33]=[CH:32][C:31]([O:21][C:22]4[CH:23]=[CH:24][C:25]([C:26]([OH:28])=[O:27])=[CH:29][CH:30]=4)=[CH:39][CH:38]=3)=[O:37])=[CH:3][CH:4]=2)[C:16]1=[O:17]

Participants

5

Reactant 3

HCID 7504BenzylamineHCID 751834,4'-Oxydibenzoic acidHCID 86591936HCID 86591936, compound

Product 2

HCID 21083189HCID 21083189, compoundHCID 86591936HCID 86591936, compound

Procedure

The benzylamine from ha was reacted with the 2,3,4,5,6-pentahydroxyhexylamide of 4,4′-oxybisbenzoic acid from If as described in Example I. This produced the 2,3,4,5,6-pentahydroxyhexylamide of 4-(4-{4-[3-(3-hydroxy-3-phenylpropyl)-2-oxo-4-phenylazetidin-1-yl]benzylcarbamoyl}phenoxy)benzoic acid (9) of molecular weight 789.89 (C45H47N3O10); MS (ESI): 790.26 (MH+).

Sources & evidence

ORD record
ord-af0640be9ec94c47b5cfff9fa2115230
Source dataset
uspto-grants-2008_06
Patent number
US07390790B2

Reaction notes

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