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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 13372Generated: October 25, 2026

2-Fluorophenol → 5-(2-Fluoro-phenoxy)-2-pyridin-2-yl-6-(4-methanesulfonyl-phenoxy)-1H-benzimidazole

https://huagongshe.com/reaction/13372

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-FluorophenolHCID 9707—
Reactant5-(2-Ethoxycarbonyl-phenoxy)-6-(4-methanesulfonyl-phenoxy)-2-pyridin-2-yl-1H-benzimidazoleHCID 23145140—
Product5-(2-Fluoro-phenoxy)-2-pyridin-2-yl-6-(4-methanesulfonyl-phenoxy)-1H-benzimidazoleHCID 23145540—

Reaction Steps

The entitled compound was obtained as a colorless solid in the same method as in Example 196 (step 4) to (step 6) or in accordance with the method or by combining it with an ordinary method but using 5-fluoro-4-(4-methanesulfonyl-phenoxy)-2-nitro-phenylamine obtained in Example 14 and 2-fluorophenol.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07728025B2
Source datasetuspto-grants-2010_06
ORD IDord-3cf2e11f49db4a2eb9c671ea18a3af36
Source noteuspto-grants-2010_06