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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1337726Generated: October 29, 2026

3-Bromopyridine → 3-(4-Phenyl-1-piperidinyl)pyridine

https://huagongshe.com/reaction/1337726

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-BromopyridineHCID 12286—
Reactant4-PhenylpiperidineHCID 69873—
Reagent2-Propanol, 2-methyl-, lithium salt (1:1)HCID 23664764—
CatalystHCID 178427212HCID 178427212—
SolventDimethyl SulfoxideHCID 679—
ProductCaffeineHCID 2519—
Product3-(4-Phenyl-1-piperidinyl)pyridineHCID 1223802235.888%
Product4-(4-Phenylpiperidin-1-yl)pyridineHCID 1398883375.66%

Reaction Conditions

Temperature30 °C

Provenance & Evidence

DOI10.1021/jacs.6c05959
Source datasetHigh-throughput exploration of 50,688 Pd-, Ni- and Cu-catalysed C–N coupling reactions
ORD IDord-5ede8b4db36a4e228144ec954fa108fb
Source noteHigh-throughput exploration of 50,688 Pd-, Ni- and Cu-catalysed C–N coupling reactions