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HRID133805

反应详情

EQUATION

反应方程式

HRID 133805 的结构方程式

REACTANTS

反应物

2
结构：COC(=O)[C@@H]1CCCN1.Cl
HCID2733200

未命名化合物

结构：CC(C)[C@@H](C(=O)O)N(C)C(=O)OC(C)(C)C
HCID7010608

Boc-N-methyl-L-valine

C11H21NO4

PRODUCTS

生成物

1
结构：COC(=O)C1CCCN1C(=O)C(C(C)C)N(C)C(=O)OC(C)(C)C
HCID69018989

未命名化合物

收率 93.1%

PROCEDURE

实验过程

Using General Procedure I Method A, (2S)-(tert-Butoxycarbonyl-methyl-amino)-3-methyl-butyric acid (0.37 g, 1.6 mmol) is coupled to L-proline methyl ester hydrochloride (0.26 g, 1.6 mmol) to give 1-[2-(tert-butoxycarbonyl-methyl-amino)-3-methyl-butyryl]-pyrrolidine-2-carboxylic acid methyl ester (0.51 g, 93%) as a white solid.