HuagongsheHuagongshe Chemistry Print Report · For research reference only
Benzylamine → HCID 4672826, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Benzylamine | HCID 7504 | — |
| Reactant | 1,2-Pyrrolidinedicarboxylic acid, 1-(1,1-dimethylethyl) ester, (2S)- | HCID 85083 | — |
| Product | HCID 4672826 | HCID 4672826 | 86% |
Reaction Steps
Using General Procedure I Method A, N-(tert-butoxycarbonyl)-L-proline (1.0 g, 4.6 mmol) is coupled to benzylamine (0.55 g, 5.1 mmol) to give 1.2 g (86%) of 2-benzylcarbamoyl-pyrrolidine-1-carboxylic acid tert-butyl ester, which is submitted to the following step without further purification.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07390910B2 |
| Source dataset | uspto-grants-2008_06 |
| ORD ID | ord-8fc0a4d7a2be4e628adb6b99e2cd1734 |
| Source note | uspto-grants-2008_06 |