HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1338554Generated: October 30, 2026
3-Bromopyridine → 4-(4-Phenylpiperidin-1-yl)pyridine
https://huagongshe.com/reaction/1338554
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | 3-Bromopyridine | HCID 12286 | — |
| Reactant | 4-Phenylpiperidine | HCID 69873 | — |
| Reagent | Potassium tert-butoxide | HCID 23665647 | — |
| Catalyst | 4,4'-Bi-1,3-benzodioxole-5,5'-diylbis{bis[4-methoxy-3,5-bis(2-methyl-2-propanyl)phenyl]phosphine} | HCID 11194192 | — |
| Catalyst | HCID 178486303 | HCID 178486303 | — |
| Solvent | Dimethyl Sulfoxide | HCID 679 | — |
| Product | Caffeine | HCID 2519 | — |
| Product | 3-(4-Phenyl-1-piperidinyl)pyridine | HCID 122380223 | 21.172% |
| Product | 4-(4-Phenylpiperidin-1-yl)pyridine | HCID 139888337 | 21.198% |
Provenance & Evidence
| DOI | 10.1021/jacs.6c05959 |
|---|
| Source dataset | High-throughput exploration of 50,688 Pd-, Ni- and Cu-catalysed C–N coupling reactions |
|---|
| ORD ID | ord-0b4cc2cbe1c44fbb8906540f2fd763b6 |
|---|
| Source note | High-throughput exploration of 50,688 Pd-, Ni- and Cu-catalysed C–N coupling reactions |
|---|
